Recruitment of two dyneins to an mRNA-dependent Bicaudal D transport complex
We investigated the role of full-length Drosophila Bicaudal D (BicD) binding partners in dynein-dynactin activation for mRNA transport on microtubules. Full-length BicD robustly activated dynein-dynactin motility only when both the mRNA binding protein Egalitarian (Egl) and K10 mRNA cargo were prese...
Main Authors: | Thomas E Sladewski, Neil Billington, M Yusuf Ali, Carol S Bookwalter, Hailong Lu, Elena B Krementsova, Trina A Schroer, Kathleen M Trybus |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/36306 |
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