Ecto-5'-Nucleotidase Overexpression Reduces Tumor Growth in a Xenograph Medulloblastoma Model.

Ecto-5'-Nucleotidase Overexpression Reduces Tumor Growth in a Xenograph Medulloblastoma Model.

Ecto-5'-nucleotidase/CD73 (ecto-5'-NT) participates in extracellular ATP catabolism by converting adenosine monophosphate (AMP) into adenosine. This enzyme affects the progression and invasiveness of different tumors. Furthermore, the expression of ecto-5'-NT has also been suggested a...

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Bibliographic Details
Main Authors: Angélica R Cappellari, Micheli M Pillat, Hellio D N Souza, Fabrícia Dietrich, Francine H Oliveira, Fabrício Figueiró, Ana L Abujamra, Rafael Roesler, Joanna Lecka, Jean Sévigny, Ana Maria O Battastini, Henning Ulrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4619639?pdf=render

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http://europepmc.org/articles/PMC4619639?pdf=render

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