Ecto-5'-Nucleotidase Overexpression Reduces Tumor Growth in a Xenograph Medulloblastoma Model.
Ecto-5'-nucleotidase/CD73 (ecto-5'-NT) participates in extracellular ATP catabolism by converting adenosine monophosphate (AMP) into adenosine. This enzyme affects the progression and invasiveness of different tumors. Furthermore, the expression of ecto-5'-NT has also been suggested a...
Main Authors: | Angélica R Cappellari, Micheli M Pillat, Hellio D N Souza, Fabrícia Dietrich, Francine H Oliveira, Fabrício Figueiró, Ana L Abujamra, Rafael Roesler, Joanna Lecka, Jean Sévigny, Ana Maria O Battastini, Henning Ulrich |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4619639?pdf=render |
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