Nonsecretory Multiple Myeloma Presenting as Recurrent Vertebral Compression Fractures in an Older Male Patient

Nonsecretory multiple myeloma is a rare variant of multiple myeloma characterized by the proliferation of clonal plasma cells in the bone marrow. It is difficult to establish an early and accurate diagnosis of nonsecretory multiple myeloma because in nonsecretory myeloma cases, monoclonal immunoglob...

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Main Authors: Young Hee Maeng, Chang Lim Hyun, Sang Hoon Han, Gil Myeong Seong, Dae Hyun Song, Hyo Jung An, Hyun Min Koh
Format: Article
Language:English
Published: Korea Geriatrics Society 2018-06-01
Series:Annals of Geriatric Medicine and Research
Subjects:
Online Access:http://www.e-agmr.org/journal/view.html?doi=10.4235/agmr.2018.22.2.98
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spelling doaj-31ce4e9c3bbb42a79f66a4ff3ffe4edf2020-11-25T01:57:21ZengKorea Geriatrics SocietyAnnals of Geriatric Medicine and Research2508-47982018-06-012229810110.4235/agmr.2018.22.2.98agmr.2018.22.2.98Nonsecretory Multiple Myeloma Presenting as Recurrent Vertebral Compression Fractures in an Older Male PatientYoung Hee Maeng0Chang Lim Hyun1Sang Hoon Han2Gil Myeong Seong3Dae Hyun Song4Hyo Jung An5Hyun Min Koh6Department of Pathology, Jeju National University School of Medicine, Jeju, KoreaDepartment of Pathology, Jeju National University School of Medicine, Jeju, KoreaDepartment of Internal Medicine, Jeju National University School of Medicine, Jeju, KoreaDepartment of Internal Medicine, Jeju National University Hospital, Jeju, KoreaDepartment of Pathology, Gyeongsang National University School of Medicine, Jinju, KoreaDepartment of Pathology, Gyeongsang National University Changwon Hospital, Changwon, KoreaDepartment of Pathology, Gyeongsang National University Changwon Hospital, Changwon, KoreaNonsecretory multiple myeloma is a rare variant of multiple myeloma characterized by the proliferation of clonal plasma cells in the bone marrow. It is difficult to establish an early and accurate diagnosis of nonsecretory multiple myeloma because in nonsecretory myeloma cases, monoclonal immunoglobulin cannot be detected in the serum or urine via electrophoresis. In this report, we describe a case of nonsecretory multiple myeloma presenting as recurrent vertebral compression fractures in a 70-year-old male patient and suggest that nonsecretory multiple myeloma can be included in the differential diagnosis of multiple and recurrent vertebral compression fractures, despite the lack of detectable monoclonal immunoglobulin in the serum or urine by electrophoresis.http://www.e-agmr.org/journal/view.html?doi=10.4235/agmr.2018.22.2.98Multiple myelomaNonsecretoryVertebral compression fracture
collection DOAJ
language English
format Article
sources DOAJ
author Young Hee Maeng
Chang Lim Hyun
Sang Hoon Han
Gil Myeong Seong
Dae Hyun Song
Hyo Jung An
Hyun Min Koh
spellingShingle Young Hee Maeng
Chang Lim Hyun
Sang Hoon Han
Gil Myeong Seong
Dae Hyun Song
Hyo Jung An
Hyun Min Koh
Nonsecretory Multiple Myeloma Presenting as Recurrent Vertebral Compression Fractures in an Older Male Patient
Annals of Geriatric Medicine and Research
Multiple myeloma
Nonsecretory
Vertebral compression fracture
author_facet Young Hee Maeng
Chang Lim Hyun
Sang Hoon Han
Gil Myeong Seong
Dae Hyun Song
Hyo Jung An
Hyun Min Koh
author_sort Young Hee Maeng
title Nonsecretory Multiple Myeloma Presenting as Recurrent Vertebral Compression Fractures in an Older Male Patient
title_short Nonsecretory Multiple Myeloma Presenting as Recurrent Vertebral Compression Fractures in an Older Male Patient
title_full Nonsecretory Multiple Myeloma Presenting as Recurrent Vertebral Compression Fractures in an Older Male Patient
title_fullStr Nonsecretory Multiple Myeloma Presenting as Recurrent Vertebral Compression Fractures in an Older Male Patient
title_full_unstemmed Nonsecretory Multiple Myeloma Presenting as Recurrent Vertebral Compression Fractures in an Older Male Patient
title_sort nonsecretory multiple myeloma presenting as recurrent vertebral compression fractures in an older male patient
publisher Korea Geriatrics Society
series Annals of Geriatric Medicine and Research
issn 2508-4798
publishDate 2018-06-01
description Nonsecretory multiple myeloma is a rare variant of multiple myeloma characterized by the proliferation of clonal plasma cells in the bone marrow. It is difficult to establish an early and accurate diagnosis of nonsecretory multiple myeloma because in nonsecretory myeloma cases, monoclonal immunoglobulin cannot be detected in the serum or urine via electrophoresis. In this report, we describe a case of nonsecretory multiple myeloma presenting as recurrent vertebral compression fractures in a 70-year-old male patient and suggest that nonsecretory multiple myeloma can be included in the differential diagnosis of multiple and recurrent vertebral compression fractures, despite the lack of detectable monoclonal immunoglobulin in the serum or urine by electrophoresis.
topic Multiple myeloma
Nonsecretory
Vertebral compression fracture
url http://www.e-agmr.org/journal/view.html?doi=10.4235/agmr.2018.22.2.98
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