Synthesis and Biological Activity of Some 3-(4-(Substituted)-piperazin-1-yl)cinnolines
A new series of 6-substituted-4-methyl-3-(4-arylpiperazin-1-yl)cinnolines 8–10 were synthesized as potential antifungal agents via intramolecular cyclization of the respective 1-(2-arylhydrazono)-1-(4-arylpiperazin-1-yl)propan-2-ones 5–7, mediated by polyphosphoric acid (PPA). The amidrazones themse...
Main Authors: | Mohammad S. Mubarak, Randa G. Naffa, Ehab Q. Al-Momani, Malek A. Zihlif, Eman D. Awad, Suzan Matar, Mustafa M. El-Abadelah |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2011-12-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/17/1/227/ |
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