Poly[N-(2-aminoethyl)ethyleneimine] as a New Non-Viral Gene Delivery Carrier: The Effect of Two Protonatable Nitrogens in the Monomer Unit on Gene Delivery Efficiency

Purpose. The aim of this study was to investigate the in vitro gene delivery efficiency of poly[N-(2-aminoethyl)ethylene-imine](PAEEI), a polymer with a linear Polyethyleneimine (LPEI) backbone and with aminoethyl side groups that has two protonatable nitrogen atoms per monomer unit instead of one...

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Bibliographic Details
Main Authors: Yahya Khazaie, Farid Abedin Dorkoosh, Luis Novo, Ethlinn van Gaal, Afshin Fassihi, Seyedeh Zohreh Mirahmadi-Zareh, Mohammad Hossein Nasr Esfahani, Cornelus F. van Nostrum, Wim E. Hennink
Format: Article
Language:English
Published: Canadian Society for Pharmaceutical Sciences 2014-10-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/22285