Poly[N-(2-aminoethyl)ethyleneimine] as a New Non-Viral Gene Delivery Carrier: The Effect of Two Protonatable Nitrogens in the Monomer Unit on Gene Delivery Efficiency
Purpose. The aim of this study was to investigate the in vitro gene delivery efficiency of poly[N-(2-aminoethyl)ethylene-imine](PAEEI), a polymer with a linear Polyethyleneimine (LPEI) backbone and with aminoethyl side groups that has two protonatable nitrogen atoms per monomer unit instead of one...
Main Authors: | Yahya Khazaie, Farid Abedin Dorkoosh, Luis Novo, Ethlinn van Gaal, Afshin Fassihi, Seyedeh Zohreh Mirahmadi-Zareh, Mohammad Hossein Nasr Esfahani, Cornelus F. van Nostrum, Wim E. Hennink |
---|---|
Format: | Article |
Language: | English |
Published: |
Canadian Society for Pharmaceutical Sciences
2014-10-01
|
Series: | Journal of Pharmacy & Pharmaceutical Sciences |
Online Access: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/22285 |
Similar Items
-
Glycopolymer Polyelectrolyte Multilayers Based on Maltose-Modified Hyperbranched Poly(ethyleneimine) For Future Drug Delivery Coatings and Biomedical Applications
by: Salem, Samaa
Published: (2015) -
Effect of PEGylation on assembly morphology and cellular uptake of poly ethyleneimine-cholesterol conjugates for delivery of sorafenib tosylate in hepatocellular carcinoma
by: Maryam Monajati, et al.
Published: (2018-07-01) -
Formation of multimeric antibodies for self-delivery of active monomers
by: Yaron Dekel, et al.
Published: (2017-01-01) -
Preparation and Swelling Characteristics of Semi-interpenetrating Polymer Networks Composed of Poly(acrylamide-co-acrylic acid)/ Linear Poly(ethyleneimine) or Poly(ethyleneimine)-metal Complexes
by: D.S. Svetlichnyi, et al.
Published: (2008-01-01) -
The Effects of Poly(Ethyleneimine) (PEI) Molecular Weight on Reinforcement of Alginate Hydrogels
by: Hyun Joon Kong, et al.
Published: (2003-10-01)