Chitosan oligosaccharides attenuates oxidative-stress related retinal degeneration in rats.

This study investigated the therapeutic potential and mechanisms of chitosan oligosaccharides (COS) for oxidative stress-induced retinal diseases. Retinal oxidative damage was induced in Sprague-Dawley rats by intravitreal injection of paraquat (PQ). Low-dose (5 mg/kg) or high-dose (10 mg/kg) COS or...

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Bibliographic Details
Main Authors: I-Mo Fang, Chang-Hao Yang, Chung-May Yang, Muh-Shy Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3796472?pdf=render

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