Defining the Cholesterol Lowering Mechanism of Bergamot (<i>Citrus bergamia</i>) Extract in HepG2 and Caco-2 Cells

Defining the Cholesterol Lowering Mechanism of Bergamot (<i>Citrus bergamia</i>) Extract in HepG2 and Caco-2 Cells

Bergamot, a Mediterranean citrus fruit native to southern Italy, has been reported to have cholesterol-lowering properties; however, the mechanism of action is not well understood. Due to structural similarities with 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) inhibitors, it has been pro...

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Bibliographic Details
Main Authors: Yunying Huang, Restituto Tocmo, Mirielle C. Nauman, Monica A. Haughan, Jeremy J. Johnson
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Nutrients
Subjects:
bergamot
neohesperidin
brutieridin
cholesterol
<i>Citrus bergamia</i>
Online Access:https://www.mdpi.com/2072-6643/13/9/3156

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