Soluble epoxide hydrolase modulates immune responses in activated astrocytes involving regulation of STAT3 activity

Soluble epoxide hydrolase modulates immune responses in activated astrocytes involving regulation of STAT3 activity

Abstract Background Astrocyte activation is a common pathological feature in many brain diseases with neuroinflammation, and revealing the underlying mechanisms might shed light on the regulatory processes of the diseases. Recently, soluble epoxide hydrolase (sEH) has been proposed to affect neuroin...

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Main Authors: Chia-Chi Hung, Yi-Hsuan Lee, Yi-Min Kuo, Pei-Chien Hsu, Huey-Jen Tsay, Ying-Ting Hsu, Chih-Chin Lee, Jia-Jun Liang, Feng-Shiun Shie
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Neuroinflammation
Subjects:
Astrocyte activation
Soluble epoxide hydrolase
Immune responses
GFAP
STAT3
Online Access:http://link.springer.com/article/10.1186/s12974-019-1508-2

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