The Folding of de Novo Designed Protein DS119 via Molecular Dynamics Simulations

As they are not subjected to natural selection process, de novo designed proteins usually fold in a manner different from natural proteins. Recently, a de novo designed mini-protein DS119, with a βαβ motif and 36 amino acids, has folded unusually slowly in experiments, and transient dimers have been...

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Bibliographic Details
Main Authors: Moye Wang, Jie Hu, Zhuqing Zhang
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/17/5/612

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