Synthesis and biological evaluation of coumarin based isoxazoles, pyrimidinthiones and pyrimidin-2-ones
The titled compounds (6′a–k), (7′a–k) and (8′a–k) were synthesized from chalcones (5a–k) having coumarin moiety. Cyclization of chalcones (5a–k) with hydroxyl amine hydrochloride, thiourea and urea resulted in corresponding isoxazoles (6′a–k), pyrimidinthiones (7′a–k) and pyrimidin-2-ones (8′a–k). S...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-05-01
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| Series: | Arabian Journal of Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535214001348 |