Unexpected temporal localization of tuberculosis verrucosa cutis
Clinical forms of cutaneous tuberculosis (TB) which is a chronic granulomatous disease, varies by the route of entry into the body, the number of bacilli, its virulence and the immunological response of the body. TB verrucosa cutis (TBVC) occurs in patients who have previously been affected by tuber...
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doaj-32b482a15d0746fc8be4848d12184d6c2021-01-08T13:47:38ZengGalenos Publishing HouseTurkderm Turkish Archives of Dermatology and Venereology2651-51642020-12-0154416216410.4274/turkderm.galenos.2020.68812Unexpected temporal localization of tuberculosis verrucosa cutisSelami Aykut Temiz0https://orcid.org/0000-0003-4878-0045İlkay Özer1https://orcid.org/0000-0001-6170-0930Arzu Ataseven2https://orcid.org/0000-0001-5372-0712Recep Dursun3https://orcid.org/0000-0002-1279-574XMustafa Cihat Avunduk4https://orcid.org/0000-0002-8709-8949Ereğli State Hospital, Clinic of Dermatology, Konya, TurkeyNecmettin Erbakan University Meram Faculty of Medicine Hospital, Clinic of Dermatology, Konya, TurkeyNecmettin Erbakan University Meram Faculty of Medicine Hospital, Clinic of Dermatology, Konya, TurkeyNecmettin Erbakan University Meram Faculty of Medicine Hospital, Clinic of Dermatology, Konya, TurkeyNecmettin Erbakan University Meram Faculty of Medicine Hospital, Clinic of Pathology, Konya, TurkeyClinical forms of cutaneous tuberculosis (TB) which is a chronic granulomatous disease, varies by the route of entry into the body, the number of bacilli, its virulence and the immunological response of the body. TB verrucosa cutis (TBVC) occurs in patients who have previously been affected by tuberculosis bacilli with healthy immunity. A 68-year-old male patient was referred to our dermatology outpatient clinic from an external dermatology center with complaint of verrucous plaques on the left temporal region, persisting for two months. After a diagnosis of wart and seborrheic keratosis, cryosurgery and destructive procedures were applied to the lesions of the patient many times. Histopathological examination revealed granulomatous textures classified by infiltration of inflammatory cells around the keratin plugs and giant multinuclear cells in the epithelium sublayer, and positive staining with CD68 was detected in immunohistochemical examination. The patient was diagnosed with TBVC clinically and histopathologically. At the end of the anti-tuberculosis treatment, the lesions largely regressed with postinflammatory hyperpigmentation. Herein, we report a case of TBVC with unusual localization, which was initially misdiagnosed as wart and seborrheic keratosis. This case emphasizes the importance of differential diagnosishttp://journal.turkderm.org.tr/jvi.aspx?pdir=turkderm&plng=eng&un=TURKDERM-68812&look4=cutaneous tuberculosistuberculosis verrucosa cutiscryosurgery |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Selami Aykut Temiz İlkay Özer Arzu Ataseven Recep Dursun Mustafa Cihat Avunduk |
spellingShingle |
Selami Aykut Temiz İlkay Özer Arzu Ataseven Recep Dursun Mustafa Cihat Avunduk Unexpected temporal localization of tuberculosis verrucosa cutis Turkderm Turkish Archives of Dermatology and Venereology cutaneous tuberculosis tuberculosis verrucosa cutis cryosurgery |
author_facet |
Selami Aykut Temiz İlkay Özer Arzu Ataseven Recep Dursun Mustafa Cihat Avunduk |
author_sort |
Selami Aykut Temiz |
title |
Unexpected temporal localization of tuberculosis verrucosa cutis |
title_short |
Unexpected temporal localization of tuberculosis verrucosa cutis |
title_full |
Unexpected temporal localization of tuberculosis verrucosa cutis |
title_fullStr |
Unexpected temporal localization of tuberculosis verrucosa cutis |
title_full_unstemmed |
Unexpected temporal localization of tuberculosis verrucosa cutis |
title_sort |
unexpected temporal localization of tuberculosis verrucosa cutis |
publisher |
Galenos Publishing House |
series |
Turkderm Turkish Archives of Dermatology and Venereology |
issn |
2651-5164 |
publishDate |
2020-12-01 |
description |
Clinical forms of cutaneous tuberculosis (TB) which is a chronic granulomatous disease, varies by the route of entry into the body, the number of bacilli, its virulence and the immunological response of the body. TB verrucosa cutis (TBVC) occurs in patients who have previously been affected by tuberculosis bacilli with healthy immunity. A 68-year-old male patient was referred to our dermatology outpatient clinic from an external dermatology center with complaint of verrucous plaques on the left temporal region, persisting for two months. After a diagnosis of wart and seborrheic keratosis, cryosurgery and destructive procedures were applied to the lesions of the patient many times. Histopathological examination revealed granulomatous textures classified by infiltration of inflammatory cells around the keratin plugs and giant multinuclear cells in the epithelium sublayer, and positive staining with CD68 was detected in immunohistochemical examination. The patient was diagnosed with TBVC clinically and histopathologically. At the end of the anti-tuberculosis treatment, the lesions largely regressed with postinflammatory hyperpigmentation. Herein, we report a case of TBVC with unusual localization, which was initially misdiagnosed as wart and seborrheic keratosis. This case emphasizes the importance of differential diagnosis |
topic |
cutaneous tuberculosis tuberculosis verrucosa cutis cryosurgery |
url |
http://journal.turkderm.org.tr/jvi.aspx?pdir=turkderm&plng=eng&un=TURKDERM-68812&look4= |
work_keys_str_mv |
AT selamiaykuttemiz unexpectedtemporallocalizationoftuberculosisverrucosacutis AT ilkayozer unexpectedtemporallocalizationoftuberculosisverrucosacutis AT arzuataseven unexpectedtemporallocalizationoftuberculosisverrucosacutis AT recepdursun unexpectedtemporallocalizationoftuberculosisverrucosacutis AT mustafacihatavunduk unexpectedtemporallocalizationoftuberculosisverrucosacutis |
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