Frequency of Cervical Nodal Metastasis in Early-Stage Squamous Cell Carcinoma of the Tongue
Abstract Introduction Oral cavity carcinoma is an aggressive tumor, with the tongue being one of the most common subsites of involvement. Surgery is a gold standard method of dealing with advanced-stage tumors. However, for early-stage carcinomas of the tongue, the management remains co...
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doaj-32b9f0f641d74feeb7af3e76c75724b32020-11-25T02:38:18ZengThieme Revinter Publicações Ltda.International Archives of Otorhinolaryngology1809-97771809-48642018-04-01220213614010.1055/s-0037-1603626Frequency of Cervical Nodal Metastasis in Early-Stage Squamous Cell Carcinoma of the TongueSadaf Qadeer Ahmed0Montasir Junaid1Sohail Awan2Maliha Kazi3Hareem Usman Khan4Sohail Halim5Department of Otorhinolaryngology, Sir Syed College of Medical Sciences for Girls, Karachi, PakistanDepartment of Otorhinolaryngology, Armed Forces Hospitals Southern Region, Khamis Mushayt, Saudi ArabiaDepartment of Otorhinolaryngology, Aga Khan University, Karachi, PakistanDepartment of Otorhinolaryngology, Manchester Royal Infirmary, Manchester, United Kingdom of Great Britain and Northern IrelandDepartment of Medicine, Shifa College of Medicine, Islamabad, PakistanDepartment of Pathology, Aga Khan University, Karachi, PakistanAbstract Introduction Oral cavity carcinoma is an aggressive tumor, with the tongue being one of the most common subsites of involvement. Surgery is a gold standard method of dealing with advanced-stage tumors. However, for early-stage carcinomas of the tongue, the management remains controversial. Several studies have indicated that early-stage cancers have a high chance of occult cervical node metastasis, which, if left untreated, can greatly affect the prognosis. Certain parameters can help identify patients with occult cervical node metastases, and can avoid unnecessary neck dissection in node negative patients. Tumor thickness is one such objective parameter. Objective To estimate the frequency of cervical lymph node metastasis in patients with early-stage, node-negative (N0) squamous cell carcinoma of the tongue. Methods In-patient hospital data was reviewed from January 2013 until March 2014, and 78 patients who underwent primary resection of the tumor and neck dissection for biopsy-proven, early stage squamous cell carcinoma of the tongue were included. Data such as tumor thickness, tumor differentiation and presence of occult nodal metastasis in the surgical specimen were gathered from the histopathology reports. The frequency of subclinical cervical lymph node metastasis in patients with early-stage squamous cell carcinoma of the tongue was estimated. Results A total of 69% of the patients with tumor thicknesses > 5 mm had tumor metastases in the neck nodes, while 100% of the patients with tumor thicknesses < 5 mm had no neck nodal metastasis. Conclusion A tumor thickness > 5 mm is significantly associated with subclinical metastasis, and prophylactic neck dissection is warranted in such cases.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1603626squamous cell carcinomatongue neoplasmsneck dissection |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sadaf Qadeer Ahmed Montasir Junaid Sohail Awan Maliha Kazi Hareem Usman Khan Sohail Halim |
spellingShingle |
Sadaf Qadeer Ahmed Montasir Junaid Sohail Awan Maliha Kazi Hareem Usman Khan Sohail Halim Frequency of Cervical Nodal Metastasis in Early-Stage Squamous Cell Carcinoma of the Tongue International Archives of Otorhinolaryngology squamous cell carcinoma tongue neoplasms neck dissection |
author_facet |
Sadaf Qadeer Ahmed Montasir Junaid Sohail Awan Maliha Kazi Hareem Usman Khan Sohail Halim |
author_sort |
Sadaf Qadeer Ahmed |
title |
Frequency of Cervical Nodal Metastasis in Early-Stage Squamous Cell Carcinoma of the Tongue |
title_short |
Frequency of Cervical Nodal Metastasis in Early-Stage Squamous Cell Carcinoma of the Tongue |
title_full |
Frequency of Cervical Nodal Metastasis in Early-Stage Squamous Cell Carcinoma of the Tongue |
title_fullStr |
Frequency of Cervical Nodal Metastasis in Early-Stage Squamous Cell Carcinoma of the Tongue |
title_full_unstemmed |
Frequency of Cervical Nodal Metastasis in Early-Stage Squamous Cell Carcinoma of the Tongue |
title_sort |
frequency of cervical nodal metastasis in early-stage squamous cell carcinoma of the tongue |
publisher |
Thieme Revinter Publicações Ltda. |
series |
International Archives of Otorhinolaryngology |
issn |
1809-9777 1809-4864 |
publishDate |
2018-04-01 |
description |
Abstract
Introduction Oral cavity carcinoma is an aggressive tumor, with the tongue being one of the most common subsites of involvement. Surgery is a gold standard method of dealing with advanced-stage tumors. However, for early-stage carcinomas of the tongue, the management remains controversial. Several studies have indicated that early-stage cancers have a high chance of occult cervical node metastasis, which, if left untreated, can greatly affect the prognosis. Certain parameters can help identify patients with occult cervical node metastases, and can avoid unnecessary neck dissection in node negative patients. Tumor thickness is one such objective parameter.
Objective To estimate the frequency of cervical lymph node metastasis in patients with early-stage, node-negative (N0) squamous cell carcinoma of the tongue.
Methods In-patient hospital data was reviewed from January 2013 until March 2014, and 78 patients who underwent primary resection of the tumor and neck dissection for biopsy-proven, early stage squamous cell carcinoma of the tongue were included. Data such as tumor thickness, tumor differentiation and presence of occult nodal metastasis in the surgical specimen were gathered from the histopathology reports. The frequency of subclinical cervical lymph node metastasis in patients with early-stage squamous cell carcinoma of the tongue was estimated.
Results A total of 69% of the patients with tumor thicknesses > 5 mm had tumor metastases in the neck nodes, while 100% of the patients with tumor thicknesses < 5 mm had no neck nodal metastasis.
Conclusion A tumor thickness > 5 mm is significantly associated with subclinical metastasis, and prophylactic neck dissection is warranted in such cases. |
topic |
squamous cell carcinoma tongue neoplasms neck dissection |
url |
http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1603626 |
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