From Inflammation to Current and Alternative Therapies Involved in Wound Healing

Wound healing is a complex event that develops in three overlapping phases: inflammatory, proliferative, and remodeling. These phases are distinct in function and histological characteristics. However, they depend on the interaction of cytokines, growth factors, chemokines, and chemical mediators fr...

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Main Authors:	Mariana Barreto Serra, Wermerson Assunção Barroso, Neemias Neves da Silva, Selma do Nascimento Silva, Antonio Carlos Romão Borges, Iracelle Carvalho Abreu, Marilene Oliveira da Rocha Borges
Format:	Article
Language:	English
Published:	Hindawi Limited 2017-01-01
Series:	International Journal of Inflammation
Online Access:	http://dx.doi.org/10.1155/2017/3406215

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spelling	doaj-32d15ced80044b1f90e9facbb68022872020-11-24T23:37:55ZengHindawi LimitedInternational Journal of Inflammation2090-80402042-00992017-01-01201710.1155/2017/34062153406215From Inflammation to Current and Alternative Therapies Involved in Wound HealingMariana Barreto Serra0Wermerson Assunção Barroso1Neemias Neves da Silva2Selma do Nascimento Silva3Antonio Carlos Romão Borges4Iracelle Carvalho Abreu5Marilene Oliveira da Rocha Borges6Physiological Sciences Department, Federal University of Maranhão, São Luís, MA, BrazilPhysiological Sciences Department, Federal University of Maranhão, São Luís, MA, BrazilPhysiological Sciences Department, Federal University of Maranhão, São Luís, MA, BrazilPhysiological Sciences Department, Federal University of Maranhão, São Luís, MA, BrazilPhysiological Sciences Department, Federal University of Maranhão, São Luís, MA, BrazilPhysiological Sciences Department, Federal University of Maranhão, São Luís, MA, BrazilPhysiological Sciences Department, Federal University of Maranhão, São Luís, MA, BrazilWound healing is a complex event that develops in three overlapping phases: inflammatory, proliferative, and remodeling. These phases are distinct in function and histological characteristics. However, they depend on the interaction of cytokines, growth factors, chemokines, and chemical mediators from cells to perform regulatory events. In this article, we will review the pathway in the skin healing cascade, relating the major chemical inflammatory mediators, cellular and molecular, as well as demonstrating the local and systemic factors that interfere in healing and disorders associated with tissue repair deficiency. Finally, we will discuss the current therapeutic interventions in the wounds treatment, and the alternative therapies used as promising results in the development of new products with healing potential.http://dx.doi.org/10.1155/2017/3406215
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Mariana Barreto Serra Wermerson Assunção Barroso Neemias Neves da Silva Selma do Nascimento Silva Antonio Carlos Romão Borges Iracelle Carvalho Abreu Marilene Oliveira da Rocha Borges
spellingShingle	Mariana Barreto Serra Wermerson Assunção Barroso Neemias Neves da Silva Selma do Nascimento Silva Antonio Carlos Romão Borges Iracelle Carvalho Abreu Marilene Oliveira da Rocha Borges From Inflammation to Current and Alternative Therapies Involved in Wound Healing International Journal of Inflammation
author_facet	Mariana Barreto Serra Wermerson Assunção Barroso Neemias Neves da Silva Selma do Nascimento Silva Antonio Carlos Romão Borges Iracelle Carvalho Abreu Marilene Oliveira da Rocha Borges
author_sort	Mariana Barreto Serra
title	From Inflammation to Current and Alternative Therapies Involved in Wound Healing
title_short	From Inflammation to Current and Alternative Therapies Involved in Wound Healing
title_full	From Inflammation to Current and Alternative Therapies Involved in Wound Healing
title_fullStr	From Inflammation to Current and Alternative Therapies Involved in Wound Healing
title_full_unstemmed	From Inflammation to Current and Alternative Therapies Involved in Wound Healing
title_sort	from inflammation to current and alternative therapies involved in wound healing
publisher	Hindawi Limited
series	International Journal of Inflammation
issn	2090-8040 2042-0099
publishDate	2017-01-01
description	Wound healing is a complex event that develops in three overlapping phases: inflammatory, proliferative, and remodeling. These phases are distinct in function and histological characteristics. However, they depend on the interaction of cytokines, growth factors, chemokines, and chemical mediators from cells to perform regulatory events. In this article, we will review the pathway in the skin healing cascade, relating the major chemical inflammatory mediators, cellular and molecular, as well as demonstrating the local and systemic factors that interfere in healing and disorders associated with tissue repair deficiency. Finally, we will discuss the current therapeutic interventions in the wounds treatment, and the alternative therapies used as promising results in the development of new products with healing potential.
url	http://dx.doi.org/10.1155/2017/3406215
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From Inflammation to Current and Alternative Therapies Involved in Wound Healing

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