A prospective study of nutrition education and oral nutritional supplementation in patients with Alzheimer's disease
<p>Abstract</p> <p>Background</p> <p>Weight loss in patients with Alzheimer's disease (AD) is a common clinical manifestation that may have clinical significance.</p> <p>Objectives</p> <p>To evaluate if there is a difference between nutritio...
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doaj-32d52d7cae0b43d0a028d5cb96aaef792020-11-24T23:58:14ZengBMCNutrition Journal1475-28912011-09-011019810.1186/1475-2891-10-98A prospective study of nutrition education and oral nutritional supplementation in patients with Alzheimer's diseaseBrant César QOkamoto Ivan HNovo Neil FJuliano Yarada Silva Rosimeire VPivi Glaucia AKBertolucci Paulo HF<p>Abstract</p> <p>Background</p> <p>Weight loss in patients with Alzheimer's disease (AD) is a common clinical manifestation that may have clinical significance.</p> <p>Objectives</p> <p>To evaluate if there is a difference between nutrition education and oral nutritional supplementation on nutritional status in patients with AD.</p> <p>Methods</p> <p>A randomized, prospective 6-month study which enrolled 90 subjects with probable AD aged 65 years or older divided into 3 groups: Control Group (CG) [n = 27], Education Group (EG) [n = 25], which participated in an education program and Supplementation Group (SG) [n = 26], which received two daily servings of oral nutritional supplementation. Subjects were assessed for anthropometric data (weight, height, BMI, TSF, AC and AMC), biochemical data (total protein, albumin, and total lymphocyte count), CDR (Clinical Dementia Rating), MMSE (Mini-mental state examination), as well as dependence during meals.</p> <p>Results</p> <p>The SG showed a significant improvement in the following anthropometric measurements: weight (H calc = 22.12, p =< 0.001), BMI (H calc = 22.12, p =< 0.001), AC (H calc = 12.99, p =< 0.002), and AMC (H calc = 8.67, p =< 0.013) compared to the CG and EG. BMI of the EG was significantly greater compared to the CG. There were significant changes in total protein (H calc = 6.17, p =< 0.046), and total lymphocyte count in the SG compared to the other groups (H cal = 7.94, p = 0.019).</p> <p>Conclusion</p> <p>Oral nutritional supplementation is more effective compared to nutrition education in improving nutritional status.</p> http://www.nutritionj.com/content/10/1/98supplementationnutritional educationAlzheimer's disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Brant César Q Okamoto Ivan H Novo Neil F Juliano Yara da Silva Rosimeire V Pivi Glaucia AK Bertolucci Paulo HF |
spellingShingle |
Brant César Q Okamoto Ivan H Novo Neil F Juliano Yara da Silva Rosimeire V Pivi Glaucia AK Bertolucci Paulo HF A prospective study of nutrition education and oral nutritional supplementation in patients with Alzheimer's disease Nutrition Journal supplementation nutritional education Alzheimer's disease |
author_facet |
Brant César Q Okamoto Ivan H Novo Neil F Juliano Yara da Silva Rosimeire V Pivi Glaucia AK Bertolucci Paulo HF |
author_sort |
Brant César Q |
title |
A prospective study of nutrition education and oral nutritional supplementation in patients with Alzheimer's disease |
title_short |
A prospective study of nutrition education and oral nutritional supplementation in patients with Alzheimer's disease |
title_full |
A prospective study of nutrition education and oral nutritional supplementation in patients with Alzheimer's disease |
title_fullStr |
A prospective study of nutrition education and oral nutritional supplementation in patients with Alzheimer's disease |
title_full_unstemmed |
A prospective study of nutrition education and oral nutritional supplementation in patients with Alzheimer's disease |
title_sort |
prospective study of nutrition education and oral nutritional supplementation in patients with alzheimer's disease |
publisher |
BMC |
series |
Nutrition Journal |
issn |
1475-2891 |
publishDate |
2011-09-01 |
description |
<p>Abstract</p> <p>Background</p> <p>Weight loss in patients with Alzheimer's disease (AD) is a common clinical manifestation that may have clinical significance.</p> <p>Objectives</p> <p>To evaluate if there is a difference between nutrition education and oral nutritional supplementation on nutritional status in patients with AD.</p> <p>Methods</p> <p>A randomized, prospective 6-month study which enrolled 90 subjects with probable AD aged 65 years or older divided into 3 groups: Control Group (CG) [n = 27], Education Group (EG) [n = 25], which participated in an education program and Supplementation Group (SG) [n = 26], which received two daily servings of oral nutritional supplementation. Subjects were assessed for anthropometric data (weight, height, BMI, TSF, AC and AMC), biochemical data (total protein, albumin, and total lymphocyte count), CDR (Clinical Dementia Rating), MMSE (Mini-mental state examination), as well as dependence during meals.</p> <p>Results</p> <p>The SG showed a significant improvement in the following anthropometric measurements: weight (H calc = 22.12, p =< 0.001), BMI (H calc = 22.12, p =< 0.001), AC (H calc = 12.99, p =< 0.002), and AMC (H calc = 8.67, p =< 0.013) compared to the CG and EG. BMI of the EG was significantly greater compared to the CG. There were significant changes in total protein (H calc = 6.17, p =< 0.046), and total lymphocyte count in the SG compared to the other groups (H cal = 7.94, p = 0.019).</p> <p>Conclusion</p> <p>Oral nutritional supplementation is more effective compared to nutrition education in improving nutritional status.</p> |
topic |
supplementation nutritional education Alzheimer's disease |
url |
http://www.nutritionj.com/content/10/1/98 |
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