Prevalence and Correlates of Gastroesophageal Reflux Disease in Southern Iran: Pars Cohort Study
BACKGROUND Prevalence of gastroesophageal reflux disease (GERD) is increasing worldwide. We aimed to estimate the prevalence of GERD in Pars Cohort Study (PCS) and to find its correlates. METHODS We used the baseline data from PCS. PCS was conducted in the district of Valashahr in Fars province...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Iranian Association of Gastroenterology and Hepatology, Shiraz University of Medical Sciences
2017-07-01
|
Series: | Middle East Journal of Digestive Diseases |
Subjects: | |
Online Access: | http://www.mejdd.org/index.php/mejdd/article/view/1826 |
id |
doaj-32df226212334dfbbf6ae8a91d0af0a0 |
---|---|
record_format |
Article |
spelling |
doaj-32df226212334dfbbf6ae8a91d0af0a02020-11-25T03:51:02ZengIranian Association of Gastroenterology and Hepatology, Shiraz University of Medical SciencesMiddle East Journal of Digestive Diseases2008-52302008-52492017-07-019312913810.15171/mejdd.2017.63Prevalence and Correlates of Gastroesophageal Reflux Disease in Southern Iran: Pars Cohort StudyZohre Khodamoradi0Abdullah Gandomkar1Hossein Poustchi2Alireza Salehi3Mohammad Hadi Imanieh4Arash Etemadi5Reza Malekzadeh6MPH Department, Student Research Committee, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, IranNon-Communicable Disease Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.Digestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, IranMPH Department, Shiraz University of Medical Sciences, Shiraz, Iran.Section of Gastroenterology, Department of Pediatrics, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, IranDivision of Cancer Epidemiology and Genetics, National Center Institute, NIH, Bethesda, Maryland, USADigestive Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.BACKGROUND Prevalence of gastroesophageal reflux disease (GERD) is increasing worldwide. We aimed to estimate the prevalence of GERD in Pars Cohort Study (PCS) and to find its correlates. METHODS We used the baseline data from PCS. PCS was conducted in the district of Valashahr in Fars province in southern Iran from 2012 to 2014. 9264 inhabitants who were 40-75 years old, and agreed to participate were enrolled. Data were collected by a structured questionnaire and simple physical examination of all participants. RESULTS Generally, 58.50% (95% CI 57.49 - 59.51) of the participants had GERD and 25.10% (95% CI 24.22 - 25.99) experienced it at least weekly. Approximately, 32.0%, 52.0%, and 24.4% of the participants reported heart burn sensation, regurgitation, and both symptoms, respectively. Being female (OR: 1.45, 95% CI 1.27 - 1.65), being older (OR: 1.20, 95% CI 1.06 - 1.36), being divorced/ widowed/separated (OR: 1.38, 95% CI 1.01 - 1.91), and lower education (OR: 1.43, 95% CI 1.02 -2.03) were associated with frequent GERD. CONCLUSION GERD is common in PCS and its prevalence is close to that in western countries. Being female, higher age, being divorced/widowed/separated, lower education, history of hypertension, anxiety, insomnia, and non-cigarette tobacco smoking were associated with frequent GERD. We are going to investigate the causal relationship between these risk factors and GERD in the next stages of PCS.http://www.mejdd.org/index.php/mejdd/article/view/1826EpidemiologyGastroesophageal refluxHeartburnRegurgitationPars cohort studyIran. |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Zohre Khodamoradi Abdullah Gandomkar Hossein Poustchi Alireza Salehi Mohammad Hadi Imanieh Arash Etemadi Reza Malekzadeh |
spellingShingle |
Zohre Khodamoradi Abdullah Gandomkar Hossein Poustchi Alireza Salehi Mohammad Hadi Imanieh Arash Etemadi Reza Malekzadeh Prevalence and Correlates of Gastroesophageal Reflux Disease in Southern Iran: Pars Cohort Study Middle East Journal of Digestive Diseases Epidemiology Gastroesophageal reflux Heartburn Regurgitation Pars cohort study Iran. |
author_facet |
Zohre Khodamoradi Abdullah Gandomkar Hossein Poustchi Alireza Salehi Mohammad Hadi Imanieh Arash Etemadi Reza Malekzadeh |
author_sort |
Zohre Khodamoradi |
title |
Prevalence and Correlates of Gastroesophageal Reflux Disease in Southern Iran: Pars Cohort Study |
title_short |
Prevalence and Correlates of Gastroesophageal Reflux Disease in Southern Iran: Pars Cohort Study |
title_full |
Prevalence and Correlates of Gastroesophageal Reflux Disease in Southern Iran: Pars Cohort Study |
title_fullStr |
Prevalence and Correlates of Gastroesophageal Reflux Disease in Southern Iran: Pars Cohort Study |
title_full_unstemmed |
Prevalence and Correlates of Gastroesophageal Reflux Disease in Southern Iran: Pars Cohort Study |
title_sort |
prevalence and correlates of gastroesophageal reflux disease in southern iran: pars cohort study |
publisher |
Iranian Association of Gastroenterology and Hepatology, Shiraz University of Medical Sciences |
series |
Middle East Journal of Digestive Diseases |
issn |
2008-5230 2008-5249 |
publishDate |
2017-07-01 |
description |
BACKGROUND
Prevalence of gastroesophageal reflux disease (GERD) is increasing worldwide. We aimed to estimate the prevalence of GERD in Pars Cohort Study (PCS) and to find its correlates.
METHODS
We used the baseline data from PCS. PCS was conducted in the district of Valashahr in Fars province in southern Iran from 2012 to 2014. 9264 inhabitants who were 40-75 years old, and agreed to participate were enrolled. Data were collected by a structured questionnaire and simple physical examination of all participants.
RESULTS
Generally, 58.50% (95% CI 57.49 - 59.51) of the participants had GERD and 25.10% (95% CI 24.22 - 25.99) experienced it at least weekly. Approximately, 32.0%, 52.0%, and 24.4% of the participants reported heart burn sensation, regurgitation, and both symptoms, respectively. Being female (OR: 1.45, 95% CI 1.27 - 1.65), being older (OR: 1.20, 95% CI 1.06 - 1.36), being divorced/ widowed/separated (OR: 1.38, 95% CI 1.01 - 1.91), and lower education (OR: 1.43, 95% CI 1.02 -2.03) were associated with frequent GERD.
CONCLUSION
GERD is common in PCS and its prevalence is close to that in western countries. Being female, higher age, being divorced/widowed/separated, lower education, history of hypertension, anxiety, insomnia, and non-cigarette tobacco smoking were associated with frequent GERD. We are going to investigate the causal relationship between these risk factors and GERD in the next stages of PCS. |
topic |
Epidemiology Gastroesophageal reflux Heartburn Regurgitation Pars cohort study Iran. |
url |
http://www.mejdd.org/index.php/mejdd/article/view/1826 |
work_keys_str_mv |
AT zohrekhodamoradi prevalenceandcorrelatesofgastroesophagealrefluxdiseaseinsoutherniranparscohortstudy AT abdullahgandomkar prevalenceandcorrelatesofgastroesophagealrefluxdiseaseinsoutherniranparscohortstudy AT hosseinpoustchi prevalenceandcorrelatesofgastroesophagealrefluxdiseaseinsoutherniranparscohortstudy AT alirezasalehi prevalenceandcorrelatesofgastroesophagealrefluxdiseaseinsoutherniranparscohortstudy AT mohammadhadiimanieh prevalenceandcorrelatesofgastroesophagealrefluxdiseaseinsoutherniranparscohortstudy AT arashetemadi prevalenceandcorrelatesofgastroesophagealrefluxdiseaseinsoutherniranparscohortstudy AT rezamalekzadeh prevalenceandcorrelatesofgastroesophagealrefluxdiseaseinsoutherniranparscohortstudy |
_version_ |
1724489151803293696 |