In vitro antineoplastic effects of brivaracetam and lacosamide on human glioma cells

In vitro antineoplastic effects of brivaracetam and lacosamide on human glioma cells

Abstract Background Epilepsy is a frequent symptom in patients with glioma. Although treatment with antiepileptic drugs is generally effective in controlling seizures, drug-resistant patients are not uncommon. Multidrug resistance proteins (MRPs) and P-gp are over-represented in brain tissue of pati...

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Bibliographic Details
Main Authors: Ambra Rizzo, Sara Donzelli, Vita Girgenti, Andrea Sacconi, Chiara Vasco, Andrea Salmaggi, Giovanni Blandino, Marta Maschio, Emilio Ciusani
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Lacosamide
Brivaracetam
Brain tumor-related epilepsy
Cytotoxicity
Glioma
Online Access:http://link.springer.com/article/10.1186/s13046-017-0546-9

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