Genetic Testing in Prion Disease: Psychological Consequences of the Decisions to Know or Not to Know
Purpose: Presymptomatic testing for susceptibility to genetic prion diseases is often delivered in difficult circumstances, as the index case is often dying when a genetic diagnosis is obtained. Since test requests in these diseases are very rare, the factors underlying decisions of relatives to be...
Main Authors: | Mathias Schwartz, Jean-Philippe Brandel, Marie Lise Babonneau, Christilla Boucher, Elodie Schaerer, Stephane Haik, Jean Louis Laplanche, Marcela Gargiulo, Alexandra Durr |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-09-01
|
Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fgene.2019.00895/full |
Similar Items
-
An overview of human prion diseases
by: Imran Muhammad, et al.
Published: (2011-12-01) -
Genetic evaluation of the ovine and bovine prion protein genes (PRNP)
by: Seabury, Christopher Mark
Published: (2006) -
A case report of genetic prion disease with two different PRNP variants
by: Megan Piazza, et al.
Published: (2020-03-01) -
Novel Polymorphisms and Genetic Characteristics of the Prion Protein Gene (<i>PRNP</i>) in Dogs— A Resistant Animal of Prion Disease
by: Dong-Ju Kim, et al.
Published: (2020-06-01) -
The biological function of the cellular prion protein: an update
by: Marie-Angela Wulf, et al.
Published: (2017-05-01)