Criterion and construct validity of the CogState Schizophrenia Battery in Japanese patients with schizophrenia.

• Main Authors: Taisuke Yoshida, Motomu Suga, Kunimasa Arima, Yasuko Muranaka, Tsunehiko Tanaka, Satoshi Eguchi, Crystal Lin, Sumiko Yoshida, Masanori Ishikawa, Yuko Higuchi, Tomonori Seo, Yoshinori Ueoka, Masahito Tomotake, Yasuhiro Kaneda, David Darby, Paul Maruff, Masaomi Iyo, Kiyoto Kasai, Teruhiko Higuchi, Tomiki Sumiyoshi, Tetsuro Ohmori, Kiyohisa Takahashi, Kenji Hashimoto
• Format: Article
• Language: English
• Published: Public Library of Science (PLoS) 2011-01-01
• Series: PLoS ONE
• Online Access: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21637776/?tool=EBI

<h4>Background</h4>The CogState Schizophrenia Battery (CSB), a computerized cognitive battery, covers all the same cognitive domains as the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery but is briefer to conduct. The aim of the present study was to evaluate the criterion and construct validity of the Japanese language version of the CSB (CSB-J) in Japanese patients with schizophrenia.<h4>Methodology/principal findings</h4>Forty Japanese patients with schizophrenia and 40 Japanese healthy controls with matching age, gender, and premorbid intelligence quotient were enrolled. The CSB-J and the Brief Assessment of Cognition in Schizophrenia, Japanese-language version (BACS-J) were performed once. The structure of the CSB-J was also evaluated by a factor analysis. Similar to the BACS-J, the CSB-J was sensitive to cognitive impairment in Japanese patients with schizophrenia. Furthermore, there was a significant positive correlation between the CSB-J composite score and the BACS-J composite score. A factor analysis showed a three-factor model consisting of memory, speed, and social cognition factors.<h4>Conclusions/significance</h4>This study suggests that the CSB-J is a useful and rapid automatically administered computerized battery for assessing broad cognitive domains in Japanese patients with schizophrenia.