Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration

Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration

A configuration of a refractometer sensor is described with the aim of optically detecting the crystallization process of paracetamol. The developed sensing head is based on a conventional cleaved multi-mode fiber. The fiber tip sensor structure was submitted to contact with the liquid of interest (...

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Main Authors: Liliana Soares, Susana Novais, António Ferreira, Orlando Frazão, Susana Silva
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Sensors
Subjects:
paracetamol
crystallization
multi-mode optical fiber
Online Access:https://www.mdpi.com/1424-8220/20/1/87
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spelling doaj-332b6072dcf74f4cbc9a32cc86ec6e962020-11-25T01:06:34ZengMDPI AGSensors1424-82202019-12-012018710.3390/s20010087s20010087Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective ConfigurationLiliana Soares0Susana Novais1António Ferreira2Orlando Frazão3Susana Silva4INESC TEC—Institute for Systems and Computer Engineering, Technology and Science, Rua do Campo Alegre 687, 4169-007 Porto, PortugalINESC TEC—Institute for Systems and Computer Engineering, Technology and Science, Rua do Campo Alegre 687, 4169-007 Porto, PortugalLEPABE—Laboratory for Process Engineering, Environment, Biotechnology and Energy, Department of Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias s/n, 4200-465 Porto, PortugalINESC TEC—Institute for Systems and Computer Engineering, Technology and Science, Rua do Campo Alegre 687, 4169-007 Porto, PortugalINESC TEC—Institute for Systems and Computer Engineering, Technology and Science, Rua do Campo Alegre 687, 4169-007 Porto, PortugalA configuration of a refractometer sensor is described with the aim of optically detecting the crystallization process of paracetamol. The developed sensing head is based on a conventional cleaved multi-mode fiber. The fiber tip sensor structure was submitted to contact with the liquid of interest (paracetamol fully dissolved in 40% <i>v</i>/<i>v</i> of ethanol/water) and the crystallization process of paracetamol, induced with continued exposure to air, was monitored in real time.https://www.mdpi.com/1424-8220/20/1/87paracetamolcrystallizationmulti-mode optical fiber
collection DOAJ
language English
format Article
sources DOAJ
author Liliana Soares
Susana Novais
António Ferreira
Orlando Frazão
Susana Silva
spellingShingle Liliana Soares
Susana Novais
António Ferreira
Orlando Frazão
Susana Silva
Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration
Sensors
paracetamol
crystallization
multi-mode optical fiber
author_facet Liliana Soares
Susana Novais
António Ferreira
Orlando Frazão
Susana Silva
author_sort Liliana Soares
title Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration
title_short Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration
title_full Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration
title_fullStr Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration
title_full_unstemmed Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration
title_sort detection of the crystallization process of paracetamol with a multi-mode optical fiber in a reflective configuration
publisher MDPI AG
series Sensors
issn 1424-8220
publishDate 2019-12-01
description A configuration of a refractometer sensor is described with the aim of optically detecting the crystallization process of paracetamol. The developed sensing head is based on a conventional cleaved multi-mode fiber. The fiber tip sensor structure was submitted to contact with the liquid of interest (paracetamol fully dissolved in 40% <i>v</i>/<i>v</i> of ethanol/water) and the crystallization process of paracetamol, induced with continued exposure to air, was monitored in real time.
topic paracetamol
crystallization
multi-mode optical fiber
url https://www.mdpi.com/1424-8220/20/1/87
work_keys_str_mv AT lilianasoares detectionofthecrystallizationprocessofparacetamolwithamultimodeopticalfiberinareflectiveconfiguration
AT susananovais detectionofthecrystallizationprocessofparacetamolwithamultimodeopticalfiberinareflectiveconfiguration
AT antonioferreira detectionofthecrystallizationprocessofparacetamolwithamultimodeopticalfiberinareflectiveconfiguration
AT orlandofrazao detectionofthecrystallizationprocessofparacetamolwithamultimodeopticalfiberinareflectiveconfiguration
AT susanasilva detectionofthecrystallizationprocessofparacetamolwithamultimodeopticalfiberinareflectiveconfiguration
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