Bioinformatics analyses show dysregulation of calcium-related genes in Angelman syndrome mouse model
Background: Angelman syndrome (AS) is a genetic neurodevelopmental disorder caused by the loss of function of the UBE3A protein in the brain. In a previous study, we showed that activity-dependent calcium dynamics in hippocampal CA1 pyramidal neurons of AS mice is compromised, and its normalization...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996120304551 |