HIF-α Prolyl Hydroxylase Inhibitors and Their Implications for Biomedicine: A Comprehensive Review

HIF-α Prolyl Hydroxylase Inhibitors and Their Implications for Biomedicine: A Comprehensive Review

Oxygen is essential for the maintenance of the body. Living organisms have evolved systems to secure an oxygen environment to be proper. Hypoxia-inducible factor (HIF) plays an essential role in this process; it is a transcription factor that mediates erythropoietin (EPO) induction at the transcript...

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Bibliographic Details
Main Author:	Kiichi Hirota
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Series:	Biomedicines
Subjects:	hypoxia transcription factor hypoxia-inducible factor 1 HIF-1 hypoxia sensing HIF-PH inhibitor
Online Access:	https://www.mdpi.com/2227-9059/9/5/468

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