Functionally distinct roles for T and Tbx6 during mouse development

The mouse T-box transcription factors T and Tbx6 are co-expressed in the primitive streak and have unique domains of expression; T is expressed in the notochord, while Tbx6 is expressed in the presomitic mesoderm. T-box factors are related through a shared DNA binding domain, the T-domain, and can t...

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Bibliographic Details
Main Authors: Amy K. Wehn, Deborah R. Farkas, Carly E. Sedlock, Dibya Subedi, Deborah L. Chapman
Format: Article
Language:English
Published: The Company of Biologists 2020-08-01
Series:Biology Open
Subjects:
t
Online Access:http://bio.biologists.org/content/9/8/bio054692