Association of Anti-VEGF Injections with Progression of Geographic Atrophy

Association of Anti-VEGF Injections with Progression of Geographic Atrophy

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Age-related macular degeneration (AMD) is one of the leading causes of blindness in developed countries in people over the age of 60 years. One of the forms of advanced AMD is wet AMD. Wet AMD is a result of leakage and bleeding from abnormal neovascularization. The principal treatment for wet AMD i...

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Main Authors: Ryan Enslow, Sai Bhuvanagiri, Sravanthi Vegunta, Benjamin Cutler, Michael Neff, Brian Stagg
Format: Article
Language:English
Published: SAGE Publishing 2016-01-01
Series:Ophthalmology and Eye Diseases
Online Access:https://doi.org/10.4137/OED.S38863
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spelling doaj-336f3bacab294f8e9fac58ac4c3c651d2020-11-24T23:10:33ZengSAGE PublishingOphthalmology and Eye Diseases1179-17212016-01-01810.4137/OED.S38863Association of Anti-VEGF Injections with Progression of Geographic AtrophyRyan Enslow0Sai Bhuvanagiri1Sravanthi Vegunta2Benjamin Cutler3Michael Neff4Brian Stagg5Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA.Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA.Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA.Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA.Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA.Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, UT, USA.Age-related macular degeneration (AMD) is one of the leading causes of blindness in developed countries in people over the age of 60 years. One of the forms of advanced AMD is wet AMD. Wet AMD is a result of leakage and bleeding from abnormal neovascularization. The principal treatment for wet AMD is intravitreal anti-VEGF injections. A second form of advanced AMD is geographic atrophy (GA). GA refers to large areas of retinal pigment epithelium loss. In the literature, there is some concern that anti-VEGF injections administered to treat wet AMD may be associated with progression of GA. This review discusses evidence suggesting the association of anti-VEGF injections with progression of GA.https://doi.org/10.4137/OED.S38863
collection DOAJ
language English
format Article
sources DOAJ
author Ryan Enslow
Sai Bhuvanagiri
Sravanthi Vegunta
Benjamin Cutler
Michael Neff
Brian Stagg
spellingShingle Ryan Enslow
Sai Bhuvanagiri
Sravanthi Vegunta
Benjamin Cutler
Michael Neff
Brian Stagg
Association of Anti-VEGF Injections with Progression of Geographic Atrophy
Ophthalmology and Eye Diseases
author_facet Ryan Enslow
Sai Bhuvanagiri
Sravanthi Vegunta
Benjamin Cutler
Michael Neff
Brian Stagg
author_sort Ryan Enslow
title Association of Anti-VEGF Injections with Progression of Geographic Atrophy
title_short Association of Anti-VEGF Injections with Progression of Geographic Atrophy
title_full Association of Anti-VEGF Injections with Progression of Geographic Atrophy
title_fullStr Association of Anti-VEGF Injections with Progression of Geographic Atrophy
title_full_unstemmed Association of Anti-VEGF Injections with Progression of Geographic Atrophy
title_sort association of anti-vegf injections with progression of geographic atrophy
publisher SAGE Publishing
series Ophthalmology and Eye Diseases
issn 1179-1721
publishDate 2016-01-01
description Age-related macular degeneration (AMD) is one of the leading causes of blindness in developed countries in people over the age of 60 years. One of the forms of advanced AMD is wet AMD. Wet AMD is a result of leakage and bleeding from abnormal neovascularization. The principal treatment for wet AMD is intravitreal anti-VEGF injections. A second form of advanced AMD is geographic atrophy (GA). GA refers to large areas of retinal pigment epithelium loss. In the literature, there is some concern that anti-VEGF injections administered to treat wet AMD may be associated with progression of GA. This review discusses evidence suggesting the association of anti-VEGF injections with progression of GA.
url https://doi.org/10.4137/OED.S38863
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AT saibhuvanagiri associationofantivegfinjectionswithprogressionofgeographicatrophy
AT sravanthivegunta associationofantivegfinjectionswithprogressionofgeographicatrophy
AT benjamincutler associationofantivegfinjectionswithprogressionofgeographicatrophy
AT michaelneff associationofantivegfinjectionswithprogressionofgeographicatrophy
AT brianstagg associationofantivegfinjectionswithprogressionofgeographicatrophy
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