Chikungunya virus neutralization antigens and direct cell-to-cell transmission are revealed by human antibody-escape mutants.
Chikungunya virus (CHIKV) is an alphavirus responsible for numerous epidemics throughout Africa and Asia, causing infectious arthritis and reportedly linked with fatal infections in newborns and elderly. Previous studies in animal models indicate that humoral immunity can protect against CHIKV infec...
Main Authors: | Chia Yin Lee, Yiu-Wing Kam, Jan Fric, Benoit Malleret, Esther G L Koh, Celine Prakash, Wen Huang, Wendy W L Lee, Cui Lin, Raymond T P Lin, Laurent Renia, Cheng-I Wang, Lisa F P Ng, Lucile Warter |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-12-01
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Series: | PLoS Pathogens |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22144891/?tool=EBI |
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