Cyclodextrine Screening for the Chiral Separation of Amlodipine Enantiomers by Capillary Electrophoresis

Cyclodextrine Screening for the Chiral Separation of Amlodipine Enantiomers by Capillary Electrophoresis

Purpose: Amlodipine is a long acting, dihydropyridine type calcium channel blocker frequently used in the treatment of hypertension and coronary insufficiency. The calcium channel blocking activity resides primarily in the S-amlodipine enantiomer, while R-amlodipine is a potent inhibitor of smooth m...

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Bibliographic Details
Main Authors: Gabriel Hancu, Monica Budău, Lajos Kristóf Kántor, Anca Cârje
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2015-03-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Amlodipine
Capillary electrophoresis
Chiral Separation
Cyclodextrines
Online Access:http://apb.tbzmed.ac.ir/Portals/0/Archive/Vol5-2015/5-Hancu.pdf

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