Lasianosides F–I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of <i>Lasianthus verticillatus</i> (Lour.) Merr.

• Main Authors: Gadah Abdulaziz Al-Hamoud, Raha Saud Orfali, Yoshio Takeda, Sachiko Sugimoto, Yoshi Yamano, Nawal M. Al Musayeib, Omer Ibrahim Fantoukh, Musarat Amina, Hideaki Otsuka, Katsuyoshi Matsunami
• Format: Article
• Language: English
• Published: MDPI AG 2020-06-01
• Series: Molecules
• Subjects: Rubiaceae; iridoids; bis-iridoids; <i>Lasianthus verticillatus</i>; lasianoside
• Online Access: https://www.mdpi.com/1420-3049/25/12/2798
• ISSN: 1420-3049

A series of iridoid glycosides were isolated from the leaves of <i>Lasianthus verticillatus</i> (Lour.) Merr., belonging to family Rubiaceae. A new iridoid glycoside, lasianoside F (<b>1</b>), and three new bis-iridoid glycosides, lasianosides G–I (<b>2</b>–<b>4</b>), together with four known compounds (<b>5</b>–<b>8</b>) were isolated. The structures were established by spectroscopic methods, including 1D and 2D NMR experiments (¹H, ¹³C, DEPT, COSY, HSQC, HMBC, and NOESY) in combination with HR-ESI-MS and CD spectra.