Lasianosides F–I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of <i>Lasianthus verticillatus</i> (Lour.) Merr.

Lasianosides F–I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of <i>Lasianthus verticillatus</i> (Lour.) Merr.

A series of iridoid glycosides were isolated from the leaves of <i>Lasianthus verticillatus</i> (Lour.) Merr., belonging to family Rubiaceae. A new iridoid glycoside, lasianoside F (<b>1</b>), and three new bis-iridoid glycosides, lasianosides G–I (<b>2</b>–<b&...

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Main Authors: Gadah Abdulaziz Al-Hamoud, Raha Saud Orfali, Yoshio Takeda, Sachiko Sugimoto, Yoshi Yamano, Nawal M. Al Musayeib, Omer Ibrahim Fantoukh, Musarat Amina, Hideaki Otsuka, Katsuyoshi Matsunami
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
Rubiaceae
iridoids
bis-iridoids
<i>Lasianthus verticillatus</i>
lasianoside
Online Access:https://www.mdpi.com/1420-3049/25/12/2798
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spelling doaj-338f0b82a7ff4b0d81048729b532f3642020-11-25T03:07:16ZengMDPI AGMolecules1420-30492020-06-01252798279810.3390/molecules25122798Lasianosides F–I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of <i>Lasianthus verticillatus</i> (Lour.) Merr.Gadah Abdulaziz Al-Hamoud0Raha Saud Orfali1Yoshio Takeda2Sachiko Sugimoto3Yoshi Yamano4Nawal M. Al Musayeib5Omer Ibrahim Fantoukh6Musarat Amina7Hideaki Otsuka8Katsuyoshi Matsunami9Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11495, Saudi ArabiaDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11495, Saudi ArabiaFaculty of Integrated Arts and Sciences, The University of Tokushima, 1-1 Minamijosanjima-Cho, Tokushima 770-8502, JapanGraduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, JapanGraduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, JapanDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11495, Saudi ArabiaDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11495, Saudi ArabiaDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11495, Saudi ArabiaFaculty of Pharmacy, Yasuda Women’s University, 6-13-1 Yasuhigashi, Asaminami-ku, Hiroshima 731-0153, JapanGraduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, JapanA series of iridoid glycosides were isolated from the leaves of <i>Lasianthus verticillatus</i> (Lour.) Merr., belonging to family Rubiaceae. A new iridoid glycoside, lasianoside F (<b>1</b>), and three new bis-iridoid glycosides, lasianosides G–I (<b>2</b>–<b>4</b>), together with four known compounds (<b>5</b>–<b>8</b>) were isolated. The structures were established by spectroscopic methods, including 1D and 2D NMR experiments (<sup>1</sup>H, <sup>13</sup>C, DEPT, COSY, HSQC, HMBC, and NOESY) in combination with HR-ESI-MS and CD spectra.https://www.mdpi.com/1420-3049/25/12/2798Rubiaceaeiridoidsbis-iridoids<i>Lasianthus verticillatus</i>lasianoside
collection DOAJ
language English
format Article
sources DOAJ
author Gadah Abdulaziz Al-Hamoud
Raha Saud Orfali
Yoshio Takeda
Sachiko Sugimoto
Yoshi Yamano
Nawal M. Al Musayeib
Omer Ibrahim Fantoukh
Musarat Amina
Hideaki Otsuka
Katsuyoshi Matsunami
spellingShingle Gadah Abdulaziz Al-Hamoud
Raha Saud Orfali
Yoshio Takeda
Sachiko Sugimoto
Yoshi Yamano
Nawal M. Al Musayeib
Omer Ibrahim Fantoukh
Musarat Amina
Hideaki Otsuka
Katsuyoshi Matsunami
Lasianosides F–I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of <i>Lasianthus verticillatus</i> (Lour.) Merr.
Molecules
Rubiaceae
iridoids
bis-iridoids
<i>Lasianthus verticillatus</i>
lasianoside
author_facet Gadah Abdulaziz Al-Hamoud
Raha Saud Orfali
Yoshio Takeda
Sachiko Sugimoto
Yoshi Yamano
Nawal M. Al Musayeib
Omer Ibrahim Fantoukh
Musarat Amina
Hideaki Otsuka
Katsuyoshi Matsunami
author_sort Gadah Abdulaziz Al-Hamoud
title Lasianosides F–I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of <i>Lasianthus verticillatus</i> (Lour.) Merr.
title_short Lasianosides F–I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of <i>Lasianthus verticillatus</i> (Lour.) Merr.
title_full Lasianosides F–I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of <i>Lasianthus verticillatus</i> (Lour.) Merr.
title_fullStr Lasianosides F–I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of <i>Lasianthus verticillatus</i> (Lour.) Merr.
title_full_unstemmed Lasianosides F–I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of <i>Lasianthus verticillatus</i> (Lour.) Merr.
title_sort lasianosides f–i: a new iridoid and three new bis-iridoid glycosides from the leaves of <i>lasianthus verticillatus</i> (lour.) merr.
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2020-06-01
description A series of iridoid glycosides were isolated from the leaves of <i>Lasianthus verticillatus</i> (Lour.) Merr., belonging to family Rubiaceae. A new iridoid glycoside, lasianoside F (<b>1</b>), and three new bis-iridoid glycosides, lasianosides G–I (<b>2</b>–<b>4</b>), together with four known compounds (<b>5</b>–<b>8</b>) were isolated. The structures were established by spectroscopic methods, including 1D and 2D NMR experiments (<sup>1</sup>H, <sup>13</sup>C, DEPT, COSY, HSQC, HMBC, and NOESY) in combination with HR-ESI-MS and CD spectra.
topic Rubiaceae
iridoids
bis-iridoids
<i>Lasianthus verticillatus</i>
lasianoside
url https://www.mdpi.com/1420-3049/25/12/2798
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