Protein Expression Profiling of Giant Cell Tumors of Bone Treated with Denosumab.
Giant cell tumors of bone (GCTB) are locally aggressive osteolytic bone tumors. Recently, some clinical trials have shown that denosumab is a novel and effective therapeutic option for aggressive and recurrent GCTB. This study was performed to investigate the molecular mechanism underlying the thera...
Main Authors: | Kenta Mukaihara, Yoshiyuki Suehara, Shinji Kohsaka, Keisuke Akaike, Yu Tanabe, Daisuke Kubota, Midori Ishii, Tsutomu Fujimura, Saiko Kazuno, Taketo Okubo, Tatsuya Takagi, Takashi Yao, Kazuo Kaneko, Tsuyoshi Saito |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4749282?pdf=render |
Similar Items
-
Preoperative denosumab treatment with curettage may be a risk factor for recurrence of giant cell tumor of bone
by: Kei Sano, et al.
Published: (2020-06-01) -
Skeletal Metastasis of Unknown Primary Origin at the Initial Visit: A Retrospective Analysis of 286 Cases.
by: Tatsuya Takagi, et al.
Published: (2015-01-01) -
Cabozantinib and dastinib exert anti-tumor activity in alveolar soft part sarcoma.
by: Kenta Mukaihara, et al.
Published: (2017-01-01) -
Squamous cell carcinoma arising from chronic osteomyelitis massively expanding into the medullary cavity: A case report
by: Taisei Kurihara, et al.
Published: (2019-06-01) -
Fibrocartilaginous mesenchymoma of the tibia with predominant microcystic features: A case report and literature review
by: Tsuyoshi Saito, et al.
Published: (2019-06-01)