Interaction between obesity and the NFKB1 - 94ins/delATTG promoter polymorphism in relation to incident acute coronary syndrome: a follow up study in three independent cohorts.

Interaction between obesity and the NFKB1 - 94ins/delATTG promoter polymorphism in relation to incident acute coronary syndrome: a follow up study in three independent cohorts.

The NF-κB transcription factor family regulates several genes encoding pro-inflammatory and anti-inflammatory proteins in adipose tissues and in atherosclerotic plaques. The deletion variant allele of the NFKB1 - 94ins/delATTG promoter polymorphism leads to lower transcript levels of the p50 subunit...

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Bibliographic Details
Main Authors: Jakob Gerhard Stegger, Erik Berg Schmidt, Tina Landsvig Berentzen, Anne Tjønneland, Ulla Vogel, Eric Rimm, Thorkild I A Sørensen, Kim Overvad, Majken K Jensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3650017?pdf=render

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http://europepmc.org/articles/PMC3650017?pdf=render

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