The nucleocapsid protein of Rift Valley fever virus is a potent human CD8+ T cell antigen and elicits memory responses.

There is no licensed human vaccine currently available for Rift Valley Fever Virus (RVFV), a Category A high priority pathogen and a serious zoonotic threat. While neutralizing antibodies targeting the viral glycoproteins are protective, they appear late in the course of infection, and may not be in...

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Bibliographic Details
Main Authors: Weidong Xu, Douglas M Watts, Margaret C Costanzo, Xiaolei Tang, Leon A Venegas, Feng Jiao, Alessandro Sette, John Sidney, Andrew K Sewell, Linda Wooldridge, Shinji Makino, John C Morrill, Clarence J Peters, June Kan-Mitchell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3601065?pdf=render