Disparate volumetric fluid shifts across cerebral tissue compartments with two different anesthetics

Disparate volumetric fluid shifts across cerebral tissue compartments with two different anesthetics

Abstract Background Large differences in glymphatic system transport—similar in magnitude to those of the sleep/wake cycle—have been observed during anesthesia with dexmedetomidine supplemented with low dose isoflurane (DEXM-I) in comparison to isoflurane (ISO). However, the biophysical and bioenerg...

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Bibliographic Details
Main Authors: Burhan O. Ozturk, Brittany Monte, Sunil Koundal, Feng Dai, Helene Benveniste, Hedok Lee
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Fluids and Barriers of the CNS
Subjects:
Cerebrospinal fluid
Glymphatic transport
Anesthesia
Cerebral compartment volume
Diffusion
Solute transport
Online Access:https://doi.org/10.1186/s12987-020-00236-x

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