Extracellular DNA, cell surface proteins and c-di-GMP promote biofilm formation in Clostridioides difficile
Abstract Clostridioides difficile is the leading cause of nosocomial antibiotic-associated diarrhoea worldwide, yet there is little insight into intestinal tract colonisation and relapse. In many bacterial species, the secondary messenger cyclic-di-GMP mediates switching between planktonic phase, se...
Main Authors: | Lisa F. Dawson, Johann Peltier, Catherine L. Hall, Mark A. Harrison, Maria Derakhshan, Helen A. Shaw, Neil F. Fairweather, Brendan W. Wren |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-02-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-78437-5 |
Similar Items
-
Disparate subcellular location of putative sortase substrates in Clostridium difficile
by: Johann Peltier, et al.
Published: (2017-08-01) -
Antibiotic Resistance and Biofilm Production Capacity in Clostridioides difficile
by: Layan Abu Rahmoun, et al.
Published: (2021-08-01) -
Clostridioides difficile biofilms: A mechanism of persistence in the gut?
by: Lucy R Frost, et al.
Published: (2021-03-01) -
Characterising the role of LuxS during the biofilm formation of Clostridioides difficile
by: Slater, Ross T.
Published: (2018) -
Biofilms harbour Clostridioides difficile, serving as a reservoir for recurrent infection
by: Charmaine Normington, et al.
Published: (2021-02-01)