Underpinning heterogeneity in synaptic transmission by presynaptic ensembles of distinct morphological modules

The mechanisms underlying synaptic heterogeneity of neurotransmission at mature calyx synapses remain unclear. Here, authors identify two morphological modules that have distinct topology of calcium channel clusters and spatial coupling distance to synaptic vesicles, which may account for different...

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Bibliographic Details
Main Authors: Adam Fekete, Yukihiro Nakamura, Yi-Mei Yang, Stefan Herlitze, Melanie D. Mark, David A. DiGregorio, Lu-Yang Wang
Format: Article
Language:English
Published: Nature Publishing Group 2019-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08452-2