Metal-Bound Methisazone; Novel Drugs Targeting Prophylaxis and Treatment of SARS-CoV-2, a Molecular Docking Study

Metal-Bound Methisazone; Novel Drugs Targeting Prophylaxis and Treatment of SARS-CoV-2, a Molecular Docking Study

SARS-CoV-2 currently lacks effective first-line drug treatment. We present promising data from in silico docking studies of new Methisazone compounds (modified with calcium, Ca; iron, Fe; magnesium, Mg; manganese, Mn; or zinc, Zn) designed to bind more strongly to key proteins involved in replicatio...

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Bibliographic Details
Main Authors: Ahmed Abdelaal Ahmed Mahmoud M. Alkhatip, Michail Georgakis, Lucio R. Montero Valenzuela, Mohamed Hamza, Ehab Farag, Jaqui Hodgkinson, Hisham Hosny, Ahmed M. Kamal, Mohamed Wagih, Amr Naguib, Hany Yassin, Haytham Algameel, Mohamed Elayashy, Mohamed Abdelhaq, Mohamed I. Younis, Hassan Mohamed, Mohammed Abdulshafi, Mohamed A. Elramely
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
COVID-19
SARS-CoV-2
molecular docking
treatment
prophylaxis
Online Access:https://www.mdpi.com/1422-0067/22/6/2977

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