Clustering gene expression regulators: new approach to disease subtyping.

One of the main challenges in modern medicine is to stratify different patient groups in terms of underlying disease molecular mechanisms as to develop more personalized approach to therapy. Here we propose novel method for disease subtyping based on analysis of activated expression regulators on a...

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Bibliographic Details
Main Authors: Mikhail Pyatnitskiy, Ilya Mazo, Maria Shkrob, Elena Schwartz, Ekaterina Kotelnikova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3887006?pdf=render