Comparative Extracellular Proteomics of Aeromonas hydrophila Reveals Iron-Regulated Secreted Proteins as Potential Vaccine Candidates

Comparative Extracellular Proteomics of Aeromonas hydrophila Reveals Iron-Regulated Secreted Proteins as Potential Vaccine Candidates

In our previous study, several iron-related outer membrane proteins in Aeromonas hydrophila, a serious pathogen of farmed fish, conferred high immunoprotectivity to fish, and were proposed as potential vaccine candidates. However, the protective efficacy of these extracellular proteins against A. hy...

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Bibliographic Details
Main Authors: Yuqian Wang, Xiaoyun Wang, Farman Ali, Zeqi Li, Yuying Fu, Xiaojun Yang, Wenxiong Lin, Xiangmin Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
Aeromonas hydrophila
extracellular proteomics
iTRAQ
iron starvation
vaccine candidate
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00256/full

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