Neurodevelopmental disorder-associated ZBTB20 gene variants affect dendritic and synaptic structure.

Neurodevelopmental disorder-associated ZBTB20 gene variants affect dendritic and synaptic structure.

Dendritic spine morphology and dendritic arborization are key determinants of neuronal connectivity and play critical roles in learning, memory and behavior function. Recently, defects of ZBTB20, a BTB and zinc finger domain containing transcriptional repressor, have been implicated in a wide range...

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Bibliographic Details
Main Authors: Kelly A Jones, Yue Luo, Lynn Dukes-Rimsky, Deepak P Srivastava, Richa Koul-Tewari, Theron A Russell, Lauren P Shapiro, Anand K Srivastava, Peter Penzes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6169859?pdf=render

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http://europepmc.org/articles/PMC6169859?pdf=render

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