Extending the Effective Ranging Depth of Spectral Domain Optical Coherence Tomography by Spatial Frequency Domain Multiplexing

• Main Authors: Tong Wu, Qingqing Wang, Youwen Liu, Jiming Wang, Chongjun He, Xiaorong Gu
• Format: Article
• Language: English
• Published: MDPI AG 2016-11-01
• Series: Applied Sciences
• Subjects: fiber optics imaging; medical and biological imaging; optical coherence tomography
• Online Access: http://www.mdpi.com/2076-3417/6/11/360
• ISSN: 2076-3417

We present a spatial frequency domain multiplexing method for extending the imaging depth range of a spectral domain optical coherence tomography (SDOCT) system without any expensive device. This method uses two galvo scanners with different pivot-offset distances in two independent reference arms for spatial frequency modulation and multiplexing. The spatial frequency contents corresponding to different depth regions of the sample can be shifted to different frequency bands. The spatial frequency domain multiplexing SDOCT system provides an approximately 1.9-fold increase in the effective ranging depth compared with that of a conventional full-range SDOCT system. The reconstructed images of phantom and biological tissue demonstrate the expected increase in ranging depth. The parameters choice criterion for this method is discussed.