Lower mutation frequency of BCP/precore regions in e antigen-negative chronic HBV-infected children instead of adults patients.
To describe the Hepatitis B e antigen(HBeAg) seroconversion related mutation profiles of the basal core promoter(BCP)/precore regions in e antigen seroconverted child patients, a cohort of 245 child patients with CHB and a control patients group of 92 adult patients with CHB were recruited. The muta...
Main Authors: | Yong Huang, Haijun Deng, Xuefeng Shan, Xuyang Gong, Xiaosong Li, Zen Tu, Quanxin Long, Ailong Huang |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0120733 |
Similar Items
-
HBV subgenotypes F1b and F4 replication induces an incomplete autophagic process in hepatocytes: Role of BCP and preCore mutations.
by: María Mercedes Elizalde, et al.
Published: (2018-01-01) -
Hepatitis B virus genotype distribution and genotype-specific BCP/preCore substitutions in acute and chronic infections in Argentina.
by: María Mora González López Ledesma, et al.
Published: (2015-01-01) -
Hepatitis B Virus Genotypes and Precore/Basal Core Promoter Mutants in HBeAg Negative HBV Related
by: Chih-Lin Lin, et al.
Published: (2003) -
Analysis of HBV basal core promoter/precore gene variability in patients with HBV drug resistance and HIV co-infection in Northwest Ethiopia.
by: Yeshambel Belyhun, et al.
Published: (2018-01-01) -
Variability in the precore and core promoter regions of HBV strains in Morocco: characterization and impact on liver disease progression.
by: Bouchra Kitab, et al.
Published: (2012-01-01)