Fine needle biopsy in differential diagnosis of nodular goiter with autoimmune thyroiditis and differentiated thyroid cancers

• Main Authors: M. I. Sheremet, L. P. Sydorchuk, V. O. Shidlovskyi, A. D. Bedenyuk, A. I. Popovych, O. V. Lazaruk
• Format: Article
• Language: English
• Published: Kazimierz Wielki University 2017-04-01
• Series: Journal of Education, Health and Sport
• Subjects: nodular goiter with autoimmune thyroiditis, fine needle biopsy, apoptosis, proliferation, thyroid gland, differentiated thyroid cancer
• Online Access: http://www.ojs.ukw.edu.pl/index.php/johs/article/view/4412
• ISSN: 2391-8306

We examined 75 women with nodular NGAIT and 12 patients with differentiated thyroid cancer during 2015-2016. We have carried out an immunohistochemical study by means of monoclonal antibodies against Fas, FasL, Bcl-2, P53 and Ki67 antigens using the thyroid gland puncture material.   Thus, compared with known methods of differential diagnosis, the proposed study allows for preoperative stage, with a high probability differentiate NGAIT of DTC, by examining extracts from tissues of the thyroid gland, which, in turn, said the volume of surgery and treatment program.             Abbreviations: NGAIT - nodular goiter combined with autoimmune thyroiditis, TG – thyroid gland, PCE – preoperative cytological examination, DTC- differentiated thyroid cancer.