Chronic Fluoxetine Treatment Induces Maturation-Compatible Changes in the Dendritic Arbor and in Synaptic Responses in the Auditory Cortex

Chronic Fluoxetine Treatment Induces Maturation-Compatible Changes in the Dendritic Arbor and in Synaptic Responses in the Auditory Cortex

Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) used to treat mood and anxiety disorders. Chronic treatment with this antidepressant drug is thought to favor functional recovery by promoting structural and molecular changes in several forebrain areas. At the synaptic level, chronic flu...

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Bibliographic Details
Main Authors: Estibaliz Ampuero, Mauricio Cerda, Steffen Härtel, Francisco Javier Rubio, Solange Massa, Paula Cubillos, Lorena Abarzúa-Catalán, Rodrigo Sandoval, Albert M. Galaburda, Ursula Wyneken
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Pharmacology
Subjects:
dendritic architecture
auditory cortex
neuronal segmentation
antidepressant
NMDA receptors
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00804/full

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