Cisplatin-induced vestibular hair cell lesion-less damage at high doses
Cisplatin, a widely used anticancer drug, damages hair cells in cochlear organotypic cultures at low doses, but paradoxically causes little damage at high doses resulting in a U-shaped dose-response function. To determine if the cisplatin dose-response function for vestibular hair cells follows a si...
Main Authors: | Dalian Ding, Haiyan Jiang, Jianhui Zhang, Xianrong Xu, Weidong Qi, Haibo Shi, Shankai Yin, Richard Salvi |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-12-01
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Series: | Journal of Otology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1672293018300527 |
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