Quantifying time-varying cellular secretions with local linear models

Extracellular protein concentrations and gradients initiate a wide range of cellular responses, such as cell motility, growth, proliferation and death. Understanding inter-cellular communication requires spatio-temporal knowledge of these secreted factors and their causal relationship with cell phen...

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Bibliographic Details
Main Authors: Jeff M. Byers, Joseph A. Christodoulides, James B. Delehanty, Deepa Raghu, Marc P. Raphael
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844017302323