Chikungunya virus requires cellular chloride channels for efficient genome replication.

Chikungunya virus requires cellular chloride channels for efficient genome replication.

Chikungunya virus (CHIKV) is a re-emerging, pathogenic alphavirus that is transmitted to humans by Aedes spp. mosquitoes-causing fever and debilitating joint pain, with frequent long-term health implications and high morbidity. The CHIKV lifecycle is poorly understood and specific antiviral therapeu...

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Bibliographic Details
Main Authors: Marietta Müller, Natalie Slivinski, Eleanor J A A Todd, Henna Khalid, Raymond Li, Magdalena Karwatka, Andres Merits, Jamel Mankouri, Andrew Tuplin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007703

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