Marine Polysaccharides: A Source of Bioactive Molecules for Cell Therapy and Tissue Engineering
The therapeutic potential of natural bioactive compounds such as polysaccharides, especially glycosaminoglycans, is now well documented, and this activity combined with natural biodiversity will allow the development of a new generation of therapeutics. Advances in our understanding of the biosynthe...
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doaj-3534533c4d324e8094467989e5a2bede2020-11-24T22:20:13ZengMDPI AGMarine Drugs1660-33972011-09-01991664168110.3390/md9091664Marine Polysaccharides: A Source of Bioactive Molecules for Cell Therapy and Tissue EngineeringAnne-Marie FischerSylvia Colliec-JouaultDominique HelleyKarim SenniJessica PereiraFarida GuenicheChristine Delbarre-LadratCorinne SinquinJacqueline RatiskolGaston GodeauThe therapeutic potential of natural bioactive compounds such as polysaccharides, especially glycosaminoglycans, is now well documented, and this activity combined with natural biodiversity will allow the development of a new generation of therapeutics. Advances in our understanding of the biosynthesis, structure and function of complex glycans from mammalian origin have shown the crucial role of this class of molecules to modulate disease processes and the importance of a deeper knowledge of structure-activity relationships. Marine environment offers a tremendous biodiversity and original polysaccharides have been discovered presenting a great chemical diversity that is largely species specific. The study of the biological properties of the polysaccharides from marine eukaryotes and marine prokaryotes revealed that the polysaccharides from the marine environment could provide a valid alternative to traditional polysaccharides such as glycosaminoglycans. Marine polysaccharides present a real potential for natural product drug discovery and for the delivery of new marine derived products for therapeutic applications.http://www.mdpi.com/1660-3397/9/9/1664/marine bacteriamarine algaeexopolysaccharidessulfated polysaccharidesstructurechemical modificationbiological activityblue biotechnologycell therapytissue engineering |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Anne-Marie Fischer Sylvia Colliec-Jouault Dominique Helley Karim Senni Jessica Pereira Farida Gueniche Christine Delbarre-Ladrat Corinne Sinquin Jacqueline Ratiskol Gaston Godeau |
spellingShingle |
Anne-Marie Fischer Sylvia Colliec-Jouault Dominique Helley Karim Senni Jessica Pereira Farida Gueniche Christine Delbarre-Ladrat Corinne Sinquin Jacqueline Ratiskol Gaston Godeau Marine Polysaccharides: A Source of Bioactive Molecules for Cell Therapy and Tissue Engineering Marine Drugs marine bacteria marine algae exopolysaccharides sulfated polysaccharides structure chemical modification biological activity blue biotechnology cell therapy tissue engineering |
author_facet |
Anne-Marie Fischer Sylvia Colliec-Jouault Dominique Helley Karim Senni Jessica Pereira Farida Gueniche Christine Delbarre-Ladrat Corinne Sinquin Jacqueline Ratiskol Gaston Godeau |
author_sort |
Anne-Marie Fischer |
title |
Marine Polysaccharides: A Source of Bioactive Molecules for Cell Therapy and Tissue Engineering |
title_short |
Marine Polysaccharides: A Source of Bioactive Molecules for Cell Therapy and Tissue Engineering |
title_full |
Marine Polysaccharides: A Source of Bioactive Molecules for Cell Therapy and Tissue Engineering |
title_fullStr |
Marine Polysaccharides: A Source of Bioactive Molecules for Cell Therapy and Tissue Engineering |
title_full_unstemmed |
Marine Polysaccharides: A Source of Bioactive Molecules for Cell Therapy and Tissue Engineering |
title_sort |
marine polysaccharides: a source of bioactive molecules for cell therapy and tissue engineering |
publisher |
MDPI AG |
series |
Marine Drugs |
issn |
1660-3397 |
publishDate |
2011-09-01 |
description |
The therapeutic potential of natural bioactive compounds such as polysaccharides, especially glycosaminoglycans, is now well documented, and this activity combined with natural biodiversity will allow the development of a new generation of therapeutics. Advances in our understanding of the biosynthesis, structure and function of complex glycans from mammalian origin have shown the crucial role of this class of molecules to modulate disease processes and the importance of a deeper knowledge of structure-activity relationships. Marine environment offers a tremendous biodiversity and original polysaccharides have been discovered presenting a great chemical diversity that is largely species specific. The study of the biological properties of the polysaccharides from marine eukaryotes and marine prokaryotes revealed that the polysaccharides from the marine environment could provide a valid alternative to traditional polysaccharides such as glycosaminoglycans. Marine polysaccharides present a real potential for natural product drug discovery and for the delivery of new marine derived products for therapeutic applications. |
topic |
marine bacteria marine algae exopolysaccharides sulfated polysaccharides structure chemical modification biological activity blue biotechnology cell therapy tissue engineering |
url |
http://www.mdpi.com/1660-3397/9/9/1664/ |
work_keys_str_mv |
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