Avenanthramides Prevent Osteoblast and Osteocyte Apoptosis and Induce Osteoclast Apoptosis in Vitro in an Nrf2-Independent Manner

Avenanthramides Prevent Osteoblast and Osteocyte Apoptosis and Induce Osteoclast Apoptosis in Vitro in an Nrf2-Independent Manner

Oats contain unique bioactive compounds known as avenanthramides (AVAs) with antioxidant properties. AVAs might enhance the endogenous antioxidant cellular response by activation of the transcription factor Nrf2. Accumulation of reactive oxygen species plays a critical role in many chronic and degen...

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Bibliographic Details
Main Authors: Gretel G. Pellegrini, Cynthya C. Morales, Taylor C. Wallace, Lilian I. Plotkin, Teresita Bellido
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Nutrients
Subjects:
avenanthramides
oxidative stress
apoptosis
gene expression
bone cells
Online Access:http://www.mdpi.com/2072-6643/8/7/423

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