Kallikrein transduced mesenchymal stem cells protect against anti-GBM disease and lupus nephritis by ameliorating inflammation and oxidative stress.
Previously we have shown that kallikreins (klks) play a renoprotective role in nephrotoxic serum induced nephritis. In this study, we have used mesenchymal stem cells (MSCs) as vehicles to deliver klks into the injured kidneys and have measured their therapeutic effect on experimental antibody induc...
Main Authors: | Yajuan Li, Indu Raman, Yong Du, Mei Yan, Soyoun Min, Jichen Yang, Xiangdong Fang, Wei Li, Jianxin Lu, Xin J Zhou, Chandra Mohan, Quan-Zhen Li |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3720854?pdf=render |
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