In vitro Non-Small Cell Lung Cancer Inhibitory Effect by New Diphenylethane Isolated From Stems and Leaves of Dioscorea oppositifolia L. via ERβ-STAT3 Pathway

In vitro Non-Small Cell Lung Cancer Inhibitory Effect by New Diphenylethane Isolated From Stems and Leaves of Dioscorea oppositifolia L. via ERβ-STAT3 Pathway

Lung cancer is the most leading cause of cancer mortality throughout the world, of which about 85% cases comprise the non-small cell lung cancer (NSCLC). Estrogen and estrogen receptors are known to be involved in the pathogenesis and development of lung cancer. Dioscorea oppositifolia L. is a tradi...

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Bibliographic Details
Main Authors: Mengnan Zeng, Yingjie Ren, Beibei Zhang, Shengchao Wang, Meng Liu, Jufang Jia, Pengli Guo, Qinqin Zhang, Xiaoke Zheng, Weisheng Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Pharmacology
Subjects:
new diphenylethane
non-small cell lung cancer
ERβ
stat3
stems and leaves of Dioscorea oppositifolia L
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.622681/full

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